Anaesthetic effects of propofol polymeric micelle: a novel water soluble propofol formulation
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منابع مشابه
Anaesthetic effects of propofol polymeric micelle: a novel water soluble propofol formulation.
BACKGROUND As a result of its very low water solubility, propofol is generally presented as a lipid-based formulation with well-characterized limitations. METHODS Propofol (99.7%) was added directly to an aqueous solution of poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide)copolymers (PVP-PLA) block copolymers and stirred in order to obtain a clear solution. This formulation was filtered st...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2008
ISSN: 0007-0912
DOI: 10.1093/bja/aen147